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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BECN1 All Species: 10
Human Site: S79 Identified Species: 14.67
UniProt: Q14457 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14457 NP_003757.1 450 51896 S79 T P R Q D G V S R R F I P P A
Chimpanzee Pan troglodytes XP_511522 450 51866 S79 T P R Q D G V S R R F I P P A
Rhesus Macaque Macaca mulatta XP_001111932 450 51890 S79 T P R Q D G V S R R F I P P A
Dog Lupus familis XP_537634 362 42279 A51 G E T Q E E E A N S G E E P F
Cat Felis silvestris
Mouse Mus musculus O88597 448 51515 R113 T M E N L S R R L K V T G D L
Rat Rattus norvegicus Q91XJ1 448 51538 R113 T M E N L S R R L K V T G D L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514527 394 45783 L80 Q T D V D H P L C E E C T D T
Chicken Gallus gallus Q5ZKS6 447 51416 A83 S R R F I P P A R M M S T E S
Frog Xenopus laevis Q6GP52 445 51275 R110 T M E N L S R R L K V T G D L
Zebra Danio Brachydanio rerio P13104 284 32704
Tiger Blowfish Takifugu rubipres NP_001032963 447 51199 A83 S R K Y I P P A R M M S T E S
Fruit Fly Dros. melanogaster Q9VCE1 422 48852 M87 D G R D N K K M S A A F K L K
Honey Bee Apis mellifera XP_392365 430 49618 E82 M L V G D S G E T E S L S H H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786368 415 47747 V83 M E S L S H R V K V A S Q L F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M367 517 58486 V114 A M E E S F V V V Y K S E P V
Baker's Yeast Sacchar. cerevisiae Q02948 557 63242 T124 N K K A N S D T S D G T S T F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.7 78.8 N.A. 97.3 97.3 N.A. 76.8 91.7 88.6 20 81.1 49.1 56.4 N.A. 57.5
Protein Similarity: 100 99.7 99.7 79.5 N.A. 98 98.2 N.A. 81.5 94.6 94.8 36.4 89.5 67.7 69.3 N.A. 71.5
P-Site Identity: 100 100 100 13.3 N.A. 6.6 6.6 N.A. 6.6 13.3 6.6 0 6.6 6.6 6.6 N.A. 0
P-Site Similarity: 100 100 100 26.6 N.A. 13.3 13.3 N.A. 6.6 33.3 13.3 0 33.3 13.3 13.3 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. 28 24.2 N.A.
Protein Similarity: N.A. N.A. N.A. 45.2 44.1 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 7 0 0 0 19 0 7 13 0 0 0 19 % A
% Cys: 0 0 0 0 0 0 0 0 7 0 0 7 0 0 0 % C
% Asp: 7 0 7 7 32 0 7 0 0 7 0 0 0 25 0 % D
% Glu: 0 13 25 7 7 7 7 7 0 13 7 7 13 13 0 % E
% Phe: 0 0 0 7 0 7 0 0 0 0 19 7 0 0 19 % F
% Gly: 7 7 0 7 0 19 7 0 0 0 13 0 19 0 0 % G
% His: 0 0 0 0 0 13 0 0 0 0 0 0 0 7 7 % H
% Ile: 0 0 0 0 13 0 0 0 0 0 0 19 0 0 0 % I
% Lys: 0 7 13 0 0 7 7 0 7 19 7 0 7 0 7 % K
% Leu: 0 7 0 7 19 0 0 7 19 0 0 7 0 13 19 % L
% Met: 13 25 0 0 0 0 0 7 0 13 13 0 0 0 0 % M
% Asn: 7 0 0 19 13 0 0 0 7 0 0 0 0 0 0 % N
% Pro: 0 19 0 0 0 13 19 0 0 0 0 0 19 32 0 % P
% Gln: 7 0 0 25 0 0 0 0 0 0 0 0 7 0 0 % Q
% Arg: 0 13 32 0 0 0 25 19 32 19 0 0 0 0 0 % R
% Ser: 13 0 7 0 13 32 0 19 13 7 7 25 13 0 13 % S
% Thr: 38 7 7 0 0 0 0 7 7 0 0 25 19 7 7 % T
% Val: 0 0 7 7 0 0 25 13 7 7 19 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 0 0 0 0 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _